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Gene Expression Literature Summary
Assay
Age
Western blot
9.5 DPC

7 matching records from 7 references.

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
Sufu  SUFU negative regulator of hedgehog signaling   (Synonyms: 2810026F04Rik, b2b273Clo, Su(Fu))
Results  Reference
1J:101731 Cooper AF, Yu KP, Brueckner M, Brailey LL, Johnson L, McGrath JM, Bale AE, Cardiac and CNS defects in a mouse with targeted disruption of suppressor of fused. Development. 2005 Oct;132(19):4407-17
1J:248771 Hoelzl MA, Heby-Henricson K, Gerling M, Dias JM, Kuiper RV, Trunkle C, Bergstrom A, Ericson J, Toftgard R, Teglund S, Differential requirement of SUFU in tissue development discovered in a hypomorphic mouse model. Dev Biol. 2017 Sep 1;429(1):132-146
1J:228335 Makino S, Zhulyn O, Mo R, Puviindran V, Zhang X, Murata T, Fukumura R, Ishitsuka Y, Kotaki H, Matsumaru D, Ishii S, Hui CC, Gondo Y, T396I mutation of mouse Sufu reduces the stability and activity of Gli3 repressor. PLoS One. 2015;10(3):e0119455
1J:147574 Norman RX, Ko HW, Huang V, Eun CM, Abler LL, Zhang Z, Sun X, Eggenschwiler JT, Tubby-like protein 3 (TULP3) regulates patterning in the mouse embryo through inhibition of Hedgehog signaling. Hum Mol Genet. 2009 May 15;18(10):1740-54
1J:105832 Svard J, Henricson KH, Persson-Lek M, Rozell B, Lauth M, Bergstrom A, Ericson J, Toftgard R, Teglund S, Genetic elimination of suppressor of fused reveals an essential repressor function in the mammalian hedgehog signaling pathway. Dev Cell. 2006 Feb;10(2):187-97
1J:161408 Wang C, Pan Y, Wang B, Suppressor of fused and Spop regulate the stability, processing and function of Gli2 and Gli3 full-length activators but not their repressors. Development. 2010 Jun;137(12):2001-9
1J:219584 Zhulyn O, Hui CC, Sufu and Kif7 in limb patterning and development. Dev Dyn. 2015 Mar;244(3):468-78

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory